Tg(Pdgfrb-cre)35Vli
Transgene Detail

Summary

• Symbol: Tg(Pdgfrb-cre)35Vli
• Name: transgene insertion 35, Volkhard Lindner
• MGI ID: MGI:5291826
• Synonyms: PDGFRB-Cre(VL), Pdgfrbeta-Cre, Tg(Pdgfrb-cre)^35Vli, Tg(Pdgfrb-Cre)^45Vli
• Transgene: Tg(Pdgfrb-cre)35Vli Location: unknown
• Alliance: Tg(Pdgfrb-cre)35Vli page

Transgene origin

• Strain of Origin: FVB/N x B6;129S4-Gt(ROSA)26Sor^tm1Sor/J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdgfrb-cre)35Vli expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pdgfrb

• Mutation details: The transgenic construct contained a 4.8 kb fragment of Pdgfrb including the promoter and the first exon fused to a nuclear-targeted cre recombinase sequence. The construct was injected into fertilized oocytes. Founders were crossed to Gt(ROSA)26Sor^tm1Sor reporter mice to analyze cre activity in embryonic and adult tissues. Line 35 was used for further experiments. (J:175492)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdgfrb (species not specified) Summary of all recombinase alleles driven by Pdgfrb.

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:175492 Cuttler AS, et al., Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis. 2011 Aug;49(8):673-80
• All: 28 reference(s)