Tg(Myh6-TRPC6*)1Jmol
Transgene Detail
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Symbol: |
Tg(Myh6-TRPC6*)1Jmol |
Name: |
transgene insertion 1, Jeffery D Molkentin |
MGI ID: |
MGI:5294560 |
Synonyms: |
dnTRPC6 |
Transgene: |
Tg(Myh6-TRPC6*)1Jmol Location: unknown
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Alliance: |
Tg(Myh6-TRPC6*)1Jmol page
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Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Myh6-TRPC6*)1Jmol expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
TRPC6 (7225) |
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Mutation details: The mouse Myh6 promoter drives expression of human TRPC6 cDNA in which three highly conserved amino acids (L678-W680) within the putative pore region have been replaced by alanine (A) residues. Line 1 was generated.
(J:177257)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:177257 Hofmann T, et al., Subunit composition of mammalian transient receptor potential channels in living cells. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7461-6 |
All: |
1 reference(s) |
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