Rr17 Other Genome Feature Detail

Summary

• Symbol
  Rr17
• Name
  regulatory region 17
• Synonyms
  CNS2

• Feature Type
  enhancer
• IDs
  MGI:5313387

Location &
Maps

• Sequence Map
  Chr1:20795018-20797983 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• chr1:20795018-20797983 (GRCm39) derived from Rr17 homology arm boundaries in J:181186.

• Genetic Map
  Chromosome 1, Syntenic

Strain
Comparison

• SNPs within 2kb
  194 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  4 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a knock-out allele exhibit disrupted expression of Il17a and Il17f depending on cell type and resistance to induced experimental autoimmune encephalomyelitis.

References

• Summaries
  All 1

  Phenotypes 1
• Earliest
  J:181186 Wang X, et al., Transcription of Il17 and Il17f is controlled by conserved noncoding sequence 2. Immunity. 2012 Jan 27;36(1):23-31