Mirc15 Complex/Cluster/Region Detail

Summary

• Symbol
  Mirc15
• Name
  microRNA cluster 15, including Mir181a-2 through Mir181b-2

• Feature Type
  complex/cluster/region
• IDs
  MGI:5313567
• Cluster Members
  Mir181a-2, Mir181b-2 (2 members)

Location &
Maps

• Sequence Map
  Chr2:38742747-38743930 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic

Strain
Comparison

• SNPs within 2kb
  76 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 2 alleles in 2 genetic backgrounds
  7 phenotypes from multigenic genotypes
  8 phenotype references
  

• All Mutations and Alleles
  5
• Targeted
  5
• Find Mice (IMSR)
  2 strains or lines available

Mice homozygous for a knock-out allele exhibit normal early thymocyte development.

Other Database
Links

miRBase

MI0000223, MI0000823

References

• Summaries
  All 10

  Phenotypes 8
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:355424 Cheng HS, et al., A miRNA/CXCR4 signaling axis impairs monopoiesis and angiogenesis in diabetic critical limb ischemia. JCI Insight. 2023 Apr 10;8(7)

Mirc15 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mir181a-2, microRNA 181a-2	miRNA gene	Chr2:38742747-38742822 (+)
Mir181b-2, microRNA 181b-2	miRNA gene	Chr2:38743842-38743930 (+)