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Mirc16 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc16
  • Name
    microRNA cluster 16, including Mir181d through Mir181c
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5313570
  • Cluster Members
    Mir181d, Mir181c (2 members)
Location &
Maps
more
  • Sequence Map
    Chr8:84905345-84905590 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    109 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased CD8+ T cells.
Other Database
Links
less
miRBase MI0000724, MI0005450
References
more
  • Summaries
    All 11
    Phenotypes 9
  • Earliest
    J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
  • Latest
    J:340964 Jimenez MT, et al., The miR-181 family regulates colonic inflammation through its activity in the intestinal epithelium. J Exp Med. 2022 Dec 5;219(12)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory