Mirc19 Complex/Cluster/Region Detail

Summary

• Symbol
  Mirc19
• Name
  microRNA cluster 19, including Mir212 through Mir132

• Feature Type
  complex/cluster/region
• IDs
  MGI:5313574
• Cluster Members
  Mir212, Mir132 (2 members)

Location &
Maps

• Sequence Map
  Chr11:75064214-75064573 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, Syntenic

Strain
Comparison

• SNPs within 2kb
  63 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  15 phenotypes from 4 alleles in 3 genetic backgrounds
  25 phenotype references
  

• All Mutations and Alleles
  8
• Targeted
  8
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a knock-out allele exhibit disrupted cortical synaptic transmission and plasticity. Mice homozygous for another knock-out allele exhibit abnormal mammary gland development.

Other Database
Links

miRBase

MI0000158, MI0000696

References

• Summaries
  All 26

  Phenotypes 25
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:357960 Stojanovic T, et al., Age-Dependent and Pathway-Specific Bimodal Action of Nicotine on Synaptic Plasticity in the Hippocampus of Mice Lacking the miR-132/212 Genes. Cells. 2022 Jan 13;11(2)

Mirc19 Cluster contains:

More Data for these features

Member	Feature Type	Location
Mir212, microRNA 212	miRNA gene	Chr11:75064214-75064304 (+)
Mir132, microRNA 132	miRNA gene	Chr11:75064508-75064573 (+)