Tg(CAG-Tfb1m)AGsha
Transgene Detail

Summary

• Symbol: Tg(CAG-Tfb1m)AGsha
• Name: transgene insertion A, Gerald Shadel
• MGI ID: MGI:5313807
• Synonyms: CAG-Tfb1m, Tg-mtTFB1
• Transgene: Tg(CAG-Tfb1m)AGsha Location: unknown
• Alliance: Tg(CAG-Tfb1m)AGsha page

Transgene origin

• Strain of Origin: C57BL/6J x SJL/J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Tfb1m)AGsha expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tfb1m (MGI:2146851)

• Mutation details: The CAG-Tfb1m transgene was designed with the CMV enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter driving expression of the mitochondrial transcription factor B1 (Tfb1m) gene. Line A was established. (J:181548)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:181548 Raimundo N, et al., Mitochondrial Stress Engages E2F1 Apoptotic Signaling to Cause Deafness. Cell. 2012 Feb 17;148(4):716-26
• All: 3 reference(s)