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Mirc31 Complex/Cluster/Region Detail
Summary
  • Symbol
    Mirc31
  • Name
    microRNA cluster 31, including Mirlet7c-2 through Mirlet7b
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:5315466
  • Cluster Members
    Mirlet7c-2, Mirlet7b (2 members)
Location &
Maps
more
  • Sequence Map
    Chr15:85590804-85591604 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, Syntenic
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 3 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    25 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele of this cluster are viable.
Expression
less
  • Literature Summary
    1
Other Database
Links
less
miRBase MI0000558, MI0000560
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:358024 Erice PA, et al., Downregulation of Mirlet7 miRNA family promotes Tc17 differentiation and emphysema via de-repression of RORgammat. Elife. 2024 May 9;13
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory