Tg(tetO/CMV-Tslp)#Sfz
Transgene Detail

Summary

• Symbol: Tg(tetO/CMV-Tslp)#Sfz
• Name: transgene insertion, Steven F Ziegler
• MGI ID: MGI:5317863
• Synonyms: tetO-TSLP
• Transgene: Tg(tetO/CMV-Tslp)#Sfz Location: unknown
• Alliance: Tg(tetO/CMV-Tslp)#Sfz page

Transgene origin

• Strain of Origin: (C3H x C57BL/6)F1 x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO/CMV-Tslp)#Sfz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tslp (MGI:1855696)

• Mutation details: This transgene expresses the mouse Tslp cDNA under the control of the heptameric tetracycline operator, CMV minimal promoter, and rabbit beta-globin intron. The pound symbol (#) is used when a line is not specified and/or lines are pooled. (J:100506)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:100506 Yoo J, et al., Spontaneous atopic dermatitis in mice expressing an inducible thymic stromal lymphopoietin transgene specifically in the skin. J Exp Med. 2005 Aug 15;202(4):541-9
• All: 8 reference(s)