About   Help   FAQ
Igs1 Other Genome Feature Detail
Summary
  • Symbol
    Igs1
  • Name
    intergenic site 1
  • Synonyms
    Iis1
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:5319510
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • This insertion site is located 2 kb upstream of Ubb and is the site of integration for Tg(CAG-Bgeo/ALPP)1Lbe. Used as a neutral insertion site by Jeremy Nathans.
  • Genetic Map
    Chromosome 11, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    29 phenotypes from multigenic genotypes
    10 images
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
This marker represents an inert insertion site upstream of Ubb for targeting.
References
more
  • Summaries
    All 19
    Phenotypes 18
  • Earliest
    J:154020 Ye X, et al., Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell. 2009 Oct 16;139(2):285-98
  • Latest
    J:331973 Simonson L, et al., Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development. Development. 2022 Nov 15;149(22):dev200816
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory