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Igs1 Other Genome Feature Detail
Summary
  • Symbol
    Igs1
  • Name
    intergenic site 1
  • Synonyms
    Iis1
  • Feature Type
    unclassified other genome feature
  • IDs
    MGI:5319510
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • This insertion site is located 2 kb upstream of Ubb and is the site of integration for Tg(CAG-Bgeo/ALPP)1Lbe. Used as a neutral insertion site by Jeremy Nathans.
  • Genetic Map
    Chromosome 11, Syntenic
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    29 phenotypes from multigenic genotypes
    10 images
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
This marker represents an inert insertion site upstream of Ubb for targeting.
References
more
  • Summaries
    All 19
    Phenotypes 18
  • Earliest
    J:154020 Ye X, et al., Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell. 2009 Oct 16;139(2):285-98
  • Latest
    J:331973 Simonson L, et al., Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development. Development. 2022 Nov 15;149(22):dev200816
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory