Tg(H2-K1-HLA-A*)28Mpla
Transgene Detail

Summary

• Symbol: Tg(H2-K1-HLA-A*)28Mpla
• Name: transgene insertion 28, Marika Pla
• MGI ID: MGI:5428682
• Synonyms: A29, HLA-A29
• Transgene: Tg(H2-K1-HLA-A*)28Mpla Location: unknown
• Alliance: Tg(H2-K1-HLA-A*)28Mpla page

Transgene origin

• Strain of Origin: BALB/c and C57BL/6 and SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The H2-K1 promoter (2027 bp) drives expression of a human HLA-A*2902 cDNA followed by a simian virus 40 poly A site. (J:67871)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:67871 Szpak Y, et al., Spontaneous retinopathy in HLA-A29 transgenic mice. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2572-6
• All: 1 reference(s)