Tg(SNCA*E46K)3Elan
Transgene Detail

Summary

• Symbol: Tg(SNCA*E46K)3Elan
• Name: transgene insertion 3, Elan Pharmaceuticals Inc
• MGI ID: MGI:5431984
• Synonyms: BAC-Tg3(SNCA^E46K)
• Transgene: Tg(SNCA*E46K)3Elan Location: unknown
• Alliance: Tg(SNCA*E46K)3Elan page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(SNCA*E46K)3Elan expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: The human bacterial artificial chromosome (BAC) RP11-458H10 containing the entire SNCA, synuclein, alpha (non A4 component of amyloid precursor), gene, was modified to include the E46K mutation in exon 3. Line 3 was generated. (J:186309)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:186309 Elan Pharmaceuticals Inc, Direct Data Submission. MGI Direct Data Submission. 2012
• All: 5 reference(s)