Tg(SERPINC1-SV40)BPbr
Transgene Detail

Summary

• Symbol: Tg(SERPINC1-SV40)BPbr
• Name: transgene insertion B, Pascale Briand
• MGI ID: MGI:5437709
• Synonyms: ASV-B
• Transgene: Tg(SERPINC1-SV40)BPbr Location: unknown Genetic Position: ChrY, Syntenic
• Alliance: Tg(SERPINC1-SV40)BPbr page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene consists of the SV40 early region containing the T antigen genes under the control of 700 bp human SERPINC1 (ATIII) regulatory sequences. Northern blot analysis indicates that transgene expression is restricted to the liver. The transgene integrated on the Y chromosome. (J:101541)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:101541 Dubois N, et al., Time-course development of differentiated hepatocarcinoma and lung metastasis in transgenic mice. J Hepatol. 1991 Sep;13(2):227-39
• All: 8 reference(s)