Del(Y)2H Cytogenetic Marker Detail

Summary

• Symbol
  Del(Y)2H
• Name
  deletion, Chr Y, 2 Harwell
• Synonyms
  Y^d, Y^d-2

• Feature Type
  chromosomal deletion
• IDs
  MGI:5446731

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Y, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotypes from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

XY^Del(Y)2H and XXY^Del(Y)2H mice are female and fertile or hermaphrodite unless a second Y is present. XYY^Del(Y)2H males are sterile. The sex chromosomes segregate independently during meiosis in females with Y^Del(Y)2H.

References

• Summaries
  All 2

  Phenotypes 2
• Earliest
  J:15425 Capel B, et al., Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal. Nat Genet. 1993 Nov;5(3):301-7
• Latest
  J:29526 Laval SH, et al., Y chromosome short arm-Sxr recombination in XSxr/Y males causes deletion of Rbm and XY female sex reversal. Proc Natl Acad Sci U S A. 1995 Oct 24;92(22):10403-7