Del(Y)3H Cytogenetic Marker Detail

Summary

• Symbol
  Del(Y)3H
• Name
  deletion, Chr Y, 3 Harwell
• Synonyms
  Y^d, Y^d-3

• Feature Type
  chromosomal deletion
• IDs
  MGI:5446811

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Y, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotypes from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  0 strains or lines available

XY^Del(Y)3H and XXY^Del(Y)3H mice are female, and fertile, or hermaphrodite unless a second Y is present. XYY^Del(Y)3H males are sterile. The sex chromosomes segregate independently during meiosis in females with Y^Del(Y)3H.

References

• Summaries
  All 3

  Phenotypes 3
• Earliest
  J:15425 Capel B, et al., Deletion of Y chromosome sequences located outside the testis determining region can cause XY female sex reversal. Nat Genet. 1993 Nov;5(3):301-7
• Latest
  J:208433 Vernet N, et al., The expression of Y-linked Zfy2 in XY mouse oocytes leads to frequent meiosis 2 defects, a high incidence of subsequent early cleavage stage arrest and infertility. Development. 2014 Feb;141(4):855-66