Snord50b Gene Detail

Summary

• Symbol
  Snord50b
• Name
  small nucleolar RNA, C/D box 50B
• Synonyms
  Gm24428, mU50_v2

• Feature Type
  snoRNA gene
• IDs
  MGI:5454205
  NCBI Gene: 115487267
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr9:88403850-88403921 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 9, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  111 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5454205	snoRNA gene	Chr9:88403850-88403921 (-)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Snord50b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a null allele of both Snord50a and Snord50b exhibit enlarged spleen and swollen lymph nodes with sex-specific organ weight change.

Expression

• Literature Summary
  1

Sequences &
Gene Models

• All Sequences
  5
• RefSeq
  1

• Ensembl
  ENSMUSG00000119432 (Evidence)
• NCBI Gene
  115487267

Representative Sequences			Length	Strain/Species
genomic	115487267	NCBI Gene Model | MGI Sequence Detail	72	C57BL/6J
transcript	XR_004935898	RefSeq | MGI Sequence Detail	72	C57BL/6J

References

• Summaries
  All 5

  Developmental Gene Expression 1

  Phenotypes 1
• Earliest
  J:206419 Soeno Y, et al., Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation. PLoS One. 2013;8(8):e72105
• Latest
  J:237822 Lee J, et al., Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. J Clin Invest. 2016 Dec 01;126(12):4616-4625