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Snord50a Gene Detail
Summary
  • Symbol
    Snord50a
  • Name
    small nucleolar RNA, C/D box 50A
  • Synonyms
    Gm25122, mU50_v1
Location &
Maps
more
  • Sequence Map
    Chr9:88403582-88403653 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    114 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5454899
 snoRNA gene Chr9:88403582-88403653 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele of both Snord50a and Snord50b exhibit enlarged spleen and swollen lymph nodes with sex-specific organ weight change.
Expression
less
  • Literature Summary
    1
Sequences &
Gene Models
less
  • All Sequences
    5
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 115487269 NCBI Gene Model | MGI Sequence Detail 72 C57BL/6J ±  kb
transcript XR_004935900 RefSeq | MGI Sequence Detail 72 C57BL/6J  
For the selected sequence
References
more
  • Summaries
    All 5
    Developmental Gene Expression 1
    Phenotypes 1
  • Earliest
    J:206419 Soeno Y, et al., Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation. PLoS One. 2013;8(8):e72105
  • Latest
    J:237822 Lee J, et al., Rpl13a small nucleolar RNAs regulate systemic glucose metabolism. J Clin Invest. 2016 Dec 01;126(12):4616-4625
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory