Del(5Cyp3a57-Cyp3a59)1Mtos Cytogenetic Marker Detail

Summary

• Symbol
  Del(5Cyp3a57-Cyp3a59)1Mtos
• Name
  deletion, Chr 5, Mitsuo Oshimura 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:5469266

Location &
Maps

• Sequence Map
  Chr5:145282089-146050097 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from multigenic genotypes
  4 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 5

  Phenotypes 4
• Earliest
  J:191214 Kazuki Y, et al., Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans. Hum Mol Genet. 2013 Feb 1;22(3):578-92
• Latest
  J:344770 Hashimoto M, et al., Cyp3a deficiency enhances androgen receptor activity and cholesterol synthesis in the mouse prostate. J Steroid Biochem Mol Biol. 2016 Oct;163:121-8