Rr28 Other Genome Feature Detail

Summary

• Symbol
  Rr28
• Name
  regulatory region 28
• Synonyms
  EE, enhacer II, enhnacer I

• Feature Type
  enhancer
• IDs
  MGI:5489791

Location &
Maps

• Sequence Map
  Chr7:142122776-142124725 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• EcoRI-XbaI chr7:142121242-142124721 (GRCm39) M23358.1 chr7:142122776-142123068 M23357.1 chr7:142124459-142124725 chr7:142122776-142124725 (GRCm39)

• Genetic Map
  Chromosome 7, Syntenic

Strain
Comparison

• SNPs within 2kb
  93 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotypes from 2 alleles in 2 genetic backgrounds
  29 phenotypes from multigenic genotypes
  6 phenotype references
  

• All Mutations and Alleles
  2
• Targeted
  2
• Find Mice (IMSR)
  0 strains or lines available

Mice heterozygous for a knock-out allele in which sequence containing the H19/Igf2 endodermal enhancers was replaced with the enhancers of the endodermally expressed but not imprinted alpha-fetoprotein gene exhibit normal imprinted expression of H19 and Igf2.

References

• Summaries
  All 10

  Phenotypes 6
• Earliest
  J:30955 Yoo-Warren H, et al., Two regulatory domains flank the mouse H19 gene. Mol Cell Biol. 1988 Nov;8(11):4707-15
• Latest
  J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27