Tg(Plp1-Lmnb1)#Yfu
Transgene Detail

Summary

• Symbol: Tg(Plp1-Lmnb1)#Yfu
• Name: transgene insertion, Ying-Hui Fu
• MGI ID: MGI:5491149
• Synonyms: PLP-LMNB1^Tg
• Transgene: Tg(Plp1-Lmnb1)#Yfu Location: unknown
• Alliance: Tg(Plp1-Lmnb1)#Yfu page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Plp1-Lmnb1)#Yfu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LMNB1 (4001)

  Lmnb1

  (MGI:96795)

• Mutation details: The mouse promoter drives oligodendrocyte-specific expression of the human cDNA with a FLAG tag. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:197168)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:197168 Heng MY, et al., Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model. J Clin Invest. 2013 Jun 3;123(6):2719-29
• All: 1 reference(s)