hipr Gene Detail

Summary

• Symbol
  hipr
• Name
  highper

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:5498670
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotypes from 1 allele in 1 genetic background
  2 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (ENU)
  1
• Find Mice (IMSR)
  0 strains or lines available

Mice exhibit hyperactivity induced by cocaine, methylphenidate or alcohol with increased conditioned place preference in response to cocaine and prolonged activation of the HPA axis in response to stress.

References

• Summaries
  All 2

  Phenotypes 2
• Earliest
  J:131481 Reijmers LG, et al., A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen. Learn Mem. 2006 Mar-Apr;13(2):143-9
• Latest
  J:196485 Eisener-Dorman AF, et al., Characterization of Highper, an ENU-induced mouse mutant with abnormal psychostimulant and stress responses. Psychopharmacology (Berl). 2013 Jan;225(2):407-19