Tg(Tagln-Pth1r*)2Towl
Transgene Detail
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Symbol: |
Tg(Tagln-Pth1r*)2Towl |
Name: |
transgene insertion 2, Dwight Towler |
MGI ID: |
MGI:5509011 |
Transgene: |
Tg(Tagln-Pth1r*)2Towl Location: unknown
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Alliance: |
Tg(Tagln-Pth1r*)2Towl page
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Transgene Type: |
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Transgenic (Constitutively active, Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Tagln-Pth1r*)2Towl expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Pth1r (MGI:97801) |
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Mutation details: The vascular smooth muscle cell-specific mouse Tagln (SM22) promoter was used to drive expression of a 1.8 kb cDNA encoding the open reading frame of the H223R constitutively active form of mouse Pthr1 upstream of rabbit beta-globin 3'UTR and polyA sequences.
(J:175050)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:175050 Cheng SL, et al., Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis. Circ Res. 2010 Jul 23;107(2):271-82 |
All: |
1 reference(s) |
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