Tg(CAG-Lyn*)#Paau
Transgene Detail

Summary

• Symbol: Tg(CAG-Lyn*)#Paau
• Name: transgene insertion, Patrick Auberger
• MGI ID: MGI:5512882
• Synonyms: LynDeltaN
• Transgene: Tg(CAG-Lyn*)#Paau Location: unknown
• Alliance: Tg(CAG-Lyn*)#Paau page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Lyn*)#Paau expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Lyn

• Mutation details: This transgene consists of the cytomegalovirus enhancer, the chicken beta-actin promoter, the caspase-cleaved form of Lyn, and a rabbit beta-globin polyadenylic acid sequence. Four lines were developed. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:151886)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:151886 Marchetti S, et al., The caspase-cleaved form of LYN mediates a psoriasis-like inflammatory syndrome in mice. EMBO J. 2009 Aug 19;28(16):2449-60
• All: 2 reference(s)