Dp(16Hspa13-App)2Yah Cytogenetic Marker Detail

Summary

• Symbol
  Dp(16Hspa13-App)2Yah
• Name
  duplication, Chr 16, Yann Herault 2
• Synonyms
  Dup(16Hspa13-App)Ts2Yah, Dup(Stch-App), Dup (Stch-App)Ts2Yah, Ts2Yah

• Feature Type
  chromosomal duplication
• IDs
  MGI:5519054

Location &
Maps

• Sequence Map
  Chr16:75552078-84970840 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, Syntenic

Human Diseases

• Diseases
  1 with Dp(16Hspa13-App)2Yah mouse models

Human Disease

Mouse Models

Down syndrome

IDs

Down syndrome      

DOID:14250
ICD10CM:Q90
ICD9CM:758.0
MESH:D004314
NCI:C2993
OMIM:190685
ORDO:870
UMLS_CUI:C0013080

View 1 model

Mouse Models

Human Disease Modeled: Down syndrome

Allelic Composition	Genetic Background	Reference	Phenotypes
Dp(16Hspa13-App)2Yah/0	B6J.129P2-Dp(16Hspa13-App)2Yah	J:223518	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  10 phenotypes from 1 allele in 2 genetic backgrounds
  1 images
  6 phenotype references
  

• All Mutations and Alleles
  1
• Targeted
  1
• Find Mice (IMSR)
  1 strains or lines available

References

• Summaries
  All 6

  Diseases 1

  Phenotypes 6
• Earliest
  J:202375 Herault Y, et al., Tackling the complexity of the genotype-phenotype relationship in the Down syndrome with the mouse aneuploidy zoo: a resource of new models to study aneuploidies involving human chromosome 21. 2009;:Abstr
• Latest
  J:339533 Duchon A, et al., Multi-influential genetic interactions alter behaviour and cognition through six main biological cascades in Down syndrome mouse models. Hum Mol Genet. 2021 May 28;30(9):771-788