Rr31 Other Genome Feature Detail

Summary

• Symbol
  Rr31
• Name
  regulatory region 31
• Synonyms
  CNS(65)

• Feature Type
  enhancer
• IDs
  MGI:5523215
• Regulates expression of
  Hoxd11, Hoxd10, Hoxd9 ... (4 regulated genes)

Location &
Maps

• Sequence Map
  Chr2:75269157-75271345 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic

Strain
Comparison

• SNPs within 2kb
  168 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  4
• Targeted
  4
• Genomic Mutations
  3 involving Rr31
• Find Mice (IMSR)
  0 strains or lines available

References

• Summaries
  All 6

  Phenotypes 5
• Earliest
  J:199174 Andrey G, et al., A switch between topological domains underlies HoxD genes collinearity in mouse limbs. Science. 2013 Jun 7;340(6137):1234167
• Latest
  J:308920 Bolt CC, et al., Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations. Nat Commun. 2021 Aug 18;12(1):5013

Rr31 regulates expression of:

Feature	Feature Type	Location	Reference
Hoxd11, homeobox D11	protein coding gene	Chr2:74509902-74517360 (+)	J:199174
Hoxd10, homeobox D10	protein coding gene	Chr2:74522268-74525449 (+)	J:199174
Hoxd9, homeobox D9	protein coding gene	Chr2:74528107-74530552 (+)	J:199174
Hoxd8, homeobox D8	protein coding gene	Chr2:74534973-74538277 (+)	J:199174