Tg(MMTV-Myc*T58A)TA14Jrn
Transgene Detail

Summary

• Symbol: Tg(MMTV-Myc*T58A)TA14Jrn
• Name: transgene insertion TA14, Joseph R Nevins
• MGI ID: MGI:5524082
• Synonyms: TA14
• Transgene: Tg(MMTV-Myc*T58A)TA14Jrn Location: unknown
• Alliance: Tg(MMTV-Myc*T58A)TA14Jrn page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(MMTV-Myc*T58A)TA14Jrn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myc (MGI:97250)

• Mutation details: Myc with the T58A mutation is under the control of the MMTV promoter. Western blot analysis confirmed expression of the transgene. This is a high expressing line. (J:153233, J:193362)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:153233 Andrechek ER, et al., Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16387-92
• All: 2 reference(s)