Mir195b Gene Detail

Summary

• Symbol
  Mir195b
• Name
  microRNA 195b
• Synonyms
  mmu-mir-195b

• Feature Type
  miRNA gene
• IDs
  MGI:5530873
  NCBI Gene: 102465169
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr2:56675823-56675919 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  119 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5530873	miRNA gene	Chr2:56675823-56675919 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0008547	miRNA gene	Chr2:56265043-56265139 (+)
A/J	MGP_AJ_G0008535	miRNA gene	Chr2:54115033-54115129 (+)
AKR/J	MGP_AKRJ_G0008520	miRNA gene	Chr2:55603311-55603407 (+)
BALB/cJ	MGP_BALBcJ_G0008523	miRNA gene	Chr2:54239618-54239714 (+)
C3H/HeJ	MGP_C3HHeJ_G0008463	miRNA gene	Chr2:55682852-55682948 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0008731	miRNA gene	Chr2:57993326-57993422 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0007717	miRNA gene	Chr2:51766955-51767051 (+)
CAST/EiJ	MGP_CASTEiJ_G0008321	miRNA gene	Chr2:55700656-55700752 (+)
CBA/J	MGP_CBAJ_G0008428	miRNA gene	Chr2:60093427-60093523 (+)
DBA/2J	MGP_DBA2J_G0008466	miRNA gene	Chr2:53731390-53731486 (+)
FVB/NJ	MGP_FVBNJ_G0008483	miRNA gene	Chr2:53309622-53309718 (+)
LP/J	MGP_LPJ_G0008554	miRNA gene	Chr2:56146590-56146686 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0008445	miRNA gene	Chr2:61769286-61769382 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0008719	miRNA gene	Chr2:55579089-55579185 (+)
PWK/PhJ	MGP_PWKPhJ_G0008248	miRNA gene	Chr2:53563886-53563982 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0008106	miRNA gene	Chr2:55722346-55722442 (+)
WSB/EiJ	MGP_WSBEiJ_G0008408	miRNA gene	Chr2:55863982-55864078 (+)

Homology

• Gene Tree
  Mir195b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  3 phenotype references
  

• All Mutations and Alleles
  2
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Genomic Mutations
  1 involving Mir195b
• Find Mice (IMSR)
  0 strains or lines available

Homozygous null mice show no gross anatomical defects but aged mice have altered cell cycle regulation, metabolism, and oxidative stress markers in heart, liver, and lungs.

Expression

• Assay Results
  706
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• RefSeq
  1

• Ensembl
  ENSMUSG00000098437 (Evidence)
• NCBI Gene
  102465169

Representative Sequences			Length	Strain/Species
genomic	102465169	NCBI Gene Model | MGI Sequence Detail	97	C57BL/6J
transcript	NR_105751	RefSeq | MGI Sequence Detail	97	ZRU/MplStud

Other Database
Links

miRBase

MI0021861

References

• Summaries
  All 9

  Developmental Gene Expression 1

  Phenotypes 3
• Earliest
  J:105741 Griffiths-Jones S, et al., miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D140-4
• Latest
  J:344186 Munoz-Gallardo MDM, et al., miR-195b is required for proper cellular homeostasis in the elderly. Sci Rep. 2024 Jan 8;14(1):810