Tg(tetO-Fgf9,-EGFP)#Dor
Transgene Detail

Summary

• Symbol: Tg(tetO-Fgf9,-EGFP)#Dor
• Name: transgene insertion, David M Ornitz
• MGI ID: MGI:5538516
• Synonyms: TRE-Fgf9-IRES-eGfp
• Transgene: Tg(tetO-Fgf9,-EGFP)#Dor Location: unknown
• Alliance: Tg(tetO-Fgf9,-EGFP)#Dor page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Fgf9,-EGFP)#Dor expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fgf9 (MGI:104723)

• Mutation details: Seven tetracycline-inducible regulatory elements drive the inducible expression of Fgf9 and an enhanced green fluorescent protein reporter gene (EGFP). Crossing mice bearing this transgene with mice that express the tetracycline transactivator (tTA) or reverse transactivator (rtTA) protein under the control of a tissue-specific promoter permits regulation by tetracycline withdrawal/administration of the expression of Fgf9 and of the EGFP reporter in the progeny. Five founder lines were generated. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:107406)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:107406 White AC, et al., FGF9 and SHH signaling coordinate lung growth and development through regulation of distinct mesenchymal domains. Development. 2006 Apr;133(8):1507-17
• All: 10 reference(s)