Tg(Snca-SNCA/GFP)#Jyl
Transgene Detail

Summary

• Symbol: Tg(Snca-SNCA/GFP)#Jyl
• Name: transgene insertion, Jia-Yi Li
• MGI ID: MGI:5544077
• Transgene: Tg(Snca-SNCA/GFP)#Jyl Location: unknown
• Alliance: Tg(Snca-SNCA/GFP)#Jyl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Tg(Snca-SNCA/GFP)#Jyl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: This transgene consists of a BAC, RP23-4012, containing the whole human alpha synuclein cDNA fused to green fluorescent protein under the control of the mouse alpha synuclein promoter. Western blot analysis confirmed expression in the brain. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:197984)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:197984 Hansen C, et al., A novel alpha-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of alpha-synuclein-GFP. Neurobiol Dis. 2013 Aug;56:145-55
• All: 3 reference(s)