Tg(HBVX*,-Myc)#Skp
Transgene Detail

Summary

• Symbol: Tg(HBVX*,-Myc)#Skp
• Name: transgene insertion, Subrat Kumar Panda
• MGI ID: MGI:5544911
• Synonyms: HBx-myc, X15/myc
• Transgene: Tg(HBVX*,-Myc)#Skp Location: unknown
• Alliance: Tg(HBVX*,-Myc)#Skp page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(HBVX*,-Myc)#Skp expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Myc (MGI:97250)

• Tg(HBVX*,-Myc)#Skp expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Hepatitis B	HBVX (944566)

• Mutation details: This transgene consists of a bi-cistronic DNA construct consisting of a segment of the hepatitis B virus X gene expressing a truncated X protein (X15, amino acids 58-154) along with the murine Myc (c-myc) gene. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:81098)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:81098 Lakhtakia R, et al., Hepatocellular carcinoma in a hepatitis B 'x' transgenic mouse model: A sequential pathological evaluation. J Gastroenterol Hepatol. 2003 Jan;18(1):80-91
• All: 2 reference(s)