Gm28035 Gene Detail

Summary

• Symbol
  Gm28035
• Name
  predicted gene, 28035

• Feature Type
  protein coding gene
• IDs
  MGI:5547771
  NCBI Gene: 118451630
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr2:30130579-30172160 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  1074 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5547771	protein coding gene	Chr2:30130579-30172160 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025560	protein coding gene	Chr2:28458810-28500506 (+)
A/J	MGP_AJ_G0025538	protein coding gene	Chr2:27320098-27366558 (+)
AKR/J	MGP_AKRJ_G0025507	protein coding gene	Chr2:28256238-28298073 (+)
BALB/cJ	MGP_BALBcJ_G0025534	protein coding gene	Chr2:27448896-27490760 (+)
C3H/HeJ	MGP_C3HHeJ_G0025295	protein coding gene	Chr2:28183266-28226971 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025979	protein coding gene	Chr2:29393906-29436377 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023387	protein coding gene	Chr2:26099795-26143306 (+)
CAST/EiJ	MGP_CASTEiJ_G0024757	protein coding gene	Chr2:28076647-28120502 (+)
CBA/J	MGP_CBAJ_G0025272	protein coding gene	Chr2:30396745-30444496 (+)
DBA/2J	MGP_DBA2J_G0025405	protein coding gene	Chr2:27114243-27156347 (+)
FVB/NJ	MGP_FVBNJ_G0025368	protein coding gene	Chr2:26930274-26975135 (+)
LP/J	MGP_LPJ_G0025491	protein coding gene	Chr2:28366918-28409407 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025398	protein coding gene	Chr2:30281454-30324830 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0026037	protein coding gene	Chr2:28168994-28214088 (+)
PWK/PhJ	MGP_PWKPhJ_G0024504	protein coding gene	Chr2:26950213-26994984 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0024304	protein coding gene	Chr2:28284240-28329649 (+)
WSB/EiJ	MGP_WSBEiJ_G0024825	protein coding gene	Chr2:28294085-28337838 (+)

Homology

• Gene Tree
  Gm28035
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  3 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  1
• Gene trapped
  2
• Genomic Mutations
  1 involving Gm28035
• Find Mice (IMSR)
  0 strains or lines available

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  22
• UniProt
  1

• Ensembl
  ENSMUSG00000099041 (Evidence)
• NCBI Gene
  118451630

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000099041	Ensembl Gene Model | MGI Sequence Detail	41582	C57BL/6J
transcript	ENSMUST00000139454	Ensembl | MGI Sequence Detail	4238	Not Applicable
polypeptide	ENSMUSP00000139038	Ensembl | MGI Sequence Detail	810	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• PDB
  6FNW, 6G8Z, 6G9L, 6G9O, 6NZW, 6NZZ, 6O00, 7M17, 7M19, 7P60, 7P6K, 8B41, 8B42, 8DR8, 8DRA, 8DRE, 8DRK, 8DRN, 8DRO, 8DRQ, 8DS3, 8DS9, 8DSA, 8F74, 8F75, 8F77, 8F79, 8F7B, 8F7D, 8F7E, 8F7J
• InterPro Domains
  IPR001611 Leucine-rich repeat
  IPR050216 Leucine-rich repeat domain-containing protein
  IPR032675 Leucine-rich repeat domain superfamily
  IPR003591 Leucine-rich repeat, typical subtype
  IPR021040 LRRC8, pannexin-like TM region

References

• Summaries
  All 6

  Phenotypes 3
• Earliest
  J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

TSS for Gm28035:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr17099	Chr2:30152810-30152814 (+)	22,233 bp
Tssr17100	Chr2:30153071-30153118 (+)	22,516 bp