Tg(tetO-Rai1,-EGFP)463Walz
Transgene Detail

Summary

• Symbol: Tg(tetO-Rai1,-EGFP)463Walz
• Name: transgene insertion 463, Katherina Walz
• MGI ID: MGI:5555964
• Synonyms: I-Rai1⁴⁶³
• Transgene: Tg(tetO-Rai1,-EGFP)463Walz Location: unknown
• Alliance: Tg(tetO-Rai1,-EGFP)463Walz page

Transgene origin

• Strain of Origin: C57BL/6J x CBA/J

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence, Reporter)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Rai1,-EGFP)463Walz expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Rai1 (MGI:103291)

• Mutation details: A bidirectional tetracycline-responsive element promoter drives the inducible simultaneous expression of both murine Rai1 and EGFP. An HA tag was added to the C-terminal coding region of RAi1. This line carries six copies of the transgene. (J:207141)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:207141 Cao L, et al., Correct developmental expression level of Rai1 in forebrain neurons is required for control of body weight, activity levels and learning and memory. Hum Mol Genet. 2014 Apr 1;23(7):1771-82
• All: 1 reference(s)