Tg(KRT14-HPV8)#Vuc
Transgene Detail

Summary

• Symbol: Tg(KRT14-HPV8)#Vuc
• Name: transgene insertion, Herbert Pfister
• MGI ID: MGI:5559371
• Transgene: Tg(KRT14-HPV8)#Vuc Location: unknown
• Alliance: Tg(KRT14-HPV8)#Vuc page

Transgene origin

• Strain of Origin: (DBA x C57BL/6)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene consists of the human keratin 14 promoter, intron 2 of the rabbit beta-globin gene, the complete early region and parts of the noncoding region and the L2-open reading frame of human papillomavirus type 8 (HPV8), and keratin 14 polyadenylation sequence. The keratin 14 promoter drives expression of the transgene in basal cells of the squamous epithelium. This record represents pooled data or data where the line number is not specified. (J:96784)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:96784 Schaper ID, et al., Development of skin tumors in mice transgenic for early genes of human papillomavirus type 8. Cancer Res. 2005 Feb 15;65(4):1394-400
• All: 9 reference(s)