Tg(Cela1-luc,Cela1-TAg)#Nzh
Transgene Detail

Summary

• Symbol: Tg(Cela1-luc,Cela1-TAg)#Nzh
• Name: transgene insertion, Ning Zhang
• MGI ID: MGI:5560472
• Synonyms: EL1-luc/TAg
• Transgene: Tg(Cela1-luc,Cela1-TAg)#Nzh Location: unknown
• Alliance: Tg(Cela1-luc,Cela1-TAg)#Nzh page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: Two constructs consisting of a 216-bp rat elastase 1 promoter driving acinar cell-specific expression of luciferase and the 216-bp rat elastase 1 promoter driving acinar cell-specific expression of SV40 T and t antigens were coinjected into oocytes. Both transgenes cosegregated in subsequent generations. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:207960)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:207960 Zhang N, et al., A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging. Clin Cancer Res. 2009 Aug 1;15(15):4915-24
• All: 2 reference(s)