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Dp(16Ifnar1-Kcnj6)10Yey Cytogenetic Marker Detail
Summary
  • Symbol
    Dp(16Ifnar1-Kcnj6)10Yey
  • Name
    duplication, Chr 16, Y Eugene Yu 10
  • Feature Type
    chromosomal duplication
  • IDs
    MGI:5562361
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 16, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous for this duplication exhibit Down syndrome-associated heart defects.
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:208104 Liu C, et al., Engineered chromosome-based genetic mapping establishes a 3.7 Mb critical genomic region for Down syndrome-associated heart defects in mice. Hum Genet. 2014 Jun;133(6):743-53
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory