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Hand2os1 Gene Detail
Summary
  • Symbol
    Hand2os1
  • Name
    Hand2, opposite strand 1
  • Synonyms
    AV026068, Gm28063, Hand2-as1, Uph, upperhand
Location &
Maps
more
  • Sequence Map
    Chr8:57757296-57773894 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, Syntenic
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    404 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_5578769
 antisense lncRNA gene Chr8:57734152-57777268 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015715
 unclassified non-coding RNA gene Chr8:57015469-57032080 (-)
A/J MGP_AJ_G0015693
 unclassified non-coding RNA gene Chr8:54621995-54638704 (-)
AKR/J MGP_AKRJ_G0015656
 unclassified non-coding RNA gene Chr8:56244714-56261186 (-)
BALB/cJ MGP_BALBcJ_G0015654
 unclassified non-coding RNA gene Chr8:54936192-54953288 (-)
C3H/HeJ MGP_C3HHeJ_G0015476
 unclassified non-coding RNA gene Chr8:56901653-56918135 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016109
 unclassified non-coding RNA gene Chr8:59206855-59223450 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013837
 unclassified non-coding RNA gene Chr8:50170582-50187068 (-)
CAST/EiJ MGP_CASTEiJ_G0015031
 unclassified non-coding RNA gene Chr8:56266308-56283003 (-)
CBA/J MGP_CBAJ_G0015457
 unclassified non-coding RNA gene Chr8:61315781-61332552 (-)
DBA/2J MGP_DBA2J_G0015553
 unclassified non-coding RNA gene Chr8:54431995-54448804 (-)
FVB/NJ MGP_FVBNJ_G0015559
 unclassified non-coding RNA gene Chr8:53788644-53805102 (-)
LP/J MGP_LPJ_G0015633
 unclassified non-coding RNA gene Chr8:57033819-57050270 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015581
 unclassified non-coding RNA gene Chr8:62927820-62946424 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016151
 unclassified non-coding RNA gene Chr8:56465552-56482144 (-)
PWK/PhJ MGP_PWKPhJ_G0014812
 unclassified non-coding RNA gene Chr8:53736116-53752912 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014601
 unclassified non-coding RNA gene Chr8:55343269-55359726 (-)
WSB/EiJ MGP_WSBEiJ_G0015135
 unclassified non-coding RNA gene Chr8:56714660-56731245 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    10 phenotypes from 5 alleles in 3 genetic backgrounds
    4 phenotypes from multigenic genotypes
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozgyous for a knock-out allele exhibit pericardial effusion, growth restriction, absent right ventricle, single left-sided ventricle and embryonic lethality.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    6
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    44
  • cDNA Data
    10
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      125
    • RefSeq
      2
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 102636514 NCBI Gene Model | MGI Sequence Detail 16599 C57BL/6J ±  kb
    transcript NR_154048 RefSeq | MGI Sequence Detail 806 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 10
      Primer pair 7
      Other 1

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:2142734, MGI:5904339
    References
    more
    • Summaries
      All 18
      Developmental Gene Expression 5
      Gene Ontology 1
      Phenotypes 5
    • Earliest
      J:155956 Feng W, et al., Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. PLoS One. 2009;4(12):e8066
    • Latest
      J:345311 Ferguson CA, et al., Identification and characterization of Hand2 upstream genomic enhancers active in developing stomach and limbs. Dev Dyn. 2024 Feb;253(2):215-232
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory