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Del(6Dlx6-Dlx5)1Tlu Cytogenetic Marker Detail
Summary
  • Symbol
    Del(6Dlx6-Dlx5)1Tlu
  • Name
    deletion, Chr 6, Thomas Lufkin 1
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:5583955
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 6, Syntenic
Human Diseases
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  • Diseases
    1 with Del(6Dlx6-Dlx5)1Tlu mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    47 phenotypes from 1 allele in 2 genetic backgrounds
    4 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
References
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  • Summaries
    All 11
    Diseases 1
    Phenotypes 10
  • Earliest
    J:76480 Robledo RF, et al., The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101
  • Latest
    J:302446 Rubin AN, et al., Regulatory Elements Inserted into AAVs Confer Preferential Activity in Cortical Interneurons. eNeuro. 2020 Nov/Dec;7(6):ENEURO.0211-20.2020
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory