Gm30731 MGI Mouse Gene Detail - MGI:5589890

Symbol

Gm30731
Name

predicted gene, 30731
Synonyms

lnc-pou3f2, Pnky

Feature Type

lncRNA gene
IDs

MGI:5589890
NCBI Gene: 105500046
Alliance

gene page

Sequence Map

Chr4:22490548-22493126 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, Syntenic
Mapping Data

1 experiment

SNPs within 2kb

135 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5589890	lncRNA gene	Chr4:22490548-22493126 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0006395	lincRNA gene	Chr4:19559813-19562370 (+)
A/J	MGP_AJ_G0006387	lincRNA gene	Chr4:18975349-18977910 (+)
AKR/J	MGP_AKRJ_G0006362	lincRNA gene	Chr4:19401594-19404484 (+)
BALB/cJ	MGP_BALBcJ_G0006361	lincRNA gene	Chr4:19023683-19027003 (+)
C3H/HeJ	MGP_C3HHeJ_G0006311	lincRNA gene	Chr4:19577856-19582484 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0006528	lincRNA gene	Chr4:20321851-20324383 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0005818	lincRNA gene	Chr4:17591847-17594341 (+)
CAST/EiJ	MGP_CASTEiJ_G0006246	lincRNA gene	Chr4:19377260-19381971 (+)
CBA/J	MGP_CBAJ_G0006295	lincRNA gene	Chr4:20926175-20932068 (+)
DBA/2J	MGP_DBA2J_G0006316	lincRNA gene	Chr4:18860920-18863378 (+)
FVB/NJ	MGP_FVBNJ_G0006339	lincRNA gene	Chr4:18535957-18540468 (+)
LP/J	MGP_LPJ_G0006399	lincRNA gene	Chr4:19646734-19650551 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0006329	lincRNA gene	Chr4:22147741-22152074 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0006532	lincRNA gene	Chr4:19363152-19366223 (+)
PWK/PhJ	MGP_PWKPhJ_G0006182	lincRNA gene	Chr4:18685095-18688033 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0006095	lincRNA gene	Chr4:19190057-19192573 (+)
WSB/EiJ	MGP_WSBEiJ_G0006291	lincRNA gene	Chr4:19342790-19347187 (+)

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Gene Tree

Gm30731

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Phenotype Summary

6 phenotypes from 2 alleles in 3 genetic backgrounds
2 phenotypes from multigenic genotypes
1 phenotype reference

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

2
Targeted

2
Find Mice (IMSR)

0 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a null allele exhibit thin cerebral cortext at E13.5, reduced neuronal stem cell proliferation and neurons in the E13.5 cortical plate.

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All GO Annotations

7
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

711
Tissues

4
cDNA Data

1
Literature Summary

2

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Expression Atlas

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All Sequences

23
RefSeq

1

Ensembl

ENSMUSG00000107859 (Evidence)
NCBI Gene

105500046

Representative Sequences				Length	Strain/Species	Flank
	genomic	105500046	NCBI Gene Model \| MGI Sequence Detail	2579	C57BL/6J	± kb
	transcript	NR_131335	RefSeq \| MGI Sequence Detail	825	ZRU/MplStud

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All nucleic 1

cDNA 1

Summaries

All 5

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 1
Earliest

J:224225 Ramos AD, et al., The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells. Cell Stem Cell. 2015 Apr 2;16(4):439-47
Latest

J:281278 Andersen RE, et al., The Long Noncoding RNA Pnky Is a Trans-acting Regulator of Cortical Development In Vivo. Dev Cell. 2019 May 20;49(4):632-642.e7

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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