Cirpil Gene Detail

Summary

• Symbol
  Cirpil
• Name
  cardiac ischemia reperfusion associated p53 interacting lncRNA
• Synonyms
  Gm36149

• Feature Type
  lncRNA gene
• IDs
  MGI:5595308
  NCBI Gene: 102639960
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr5:111638797-111640250 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  113 from dbSNP Build 142
• Strain Annotations
  1

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_5595308	lncRNA gene	Chr5:111638717-111642637 (+)
129S1/SvImJ	no annotation
A/J	no annotation
AKR/J	no annotation
BALB/cJ	no annotation
C3H/HeJ	no annotation
C57BL/6NJ	no annotation
CAROLI/EiJ	no annotation
CAST/EiJ	no annotation
CBA/J	no annotation
DBA/2J	no annotation
FVB/NJ	no annotation
LP/J	no annotation
NOD/ShiLtJ	no annotation
NZO/HlLtJ	no annotation
PWK/PhJ	no annotation
SPRET/EiJ	no annotation
WSB/EiJ	no annotation

Homology

• Gene Tree
  Cirpil
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 2 alleles in 2 genetic backgrounds
  6 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Transgenic
  1
• Genomic Mutations
  2 involving Cirpil
• Find Mice (IMSR)
  0 strains or lines available

Homozygous null mice show exacerbated cardiac ischemia/reperfusion injury.

Sequences &
Gene Models

• All Sequences
  7
• RefSeq
  2

• Ensembl
  ENSMUSG00000120047 (Evidence)
• NCBI Gene
  102639960

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000120047	Ensembl Gene Model | MGI Sequence Detail	1454	C57BL/6J
transcript	ENSMUST00000244312	Ensembl | MGI Sequence Detail	1453	Not Applicable

Other
Accession IDs

MGI:7528743

References

• Summaries
  All 9

  Phenotypes 6
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:339952 Jiang Y, et al., Cytoplasmic sequestration of p53 by lncRNA-CIRPILalleviates myocardial ischemia/reperfusion injury. Commun Biol. 2022 Jul 18;5(1):716

TSS for Cirpil:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr47947	Chr5:111638787-111638824 (+)	9 bp