Tg(Camk2a-MAPT*P301L)D35Jiri
Transgene Detail

Summary

• Symbol: Tg(Camk2a-MAPT*P301L)D35Jiri
• Name: transgene insertion D35, Jill C Richardson
• MGI ID: MGI:5646621
• Synonyms: TAU, TAUD35
• Transgene: Tg(Camk2a-MAPT*P301L)D35Jiri Location: unknown
• Alliance: Tg(Camk2a-MAPT*P301L)D35Jiri page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-MAPT*P301L)D35Jiri expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MAPT (4137)

  Mapt	(MGI:97180)

  The cDNA carries the P301L mutation.

• Mutation details: The human microtubule-associated protein tau (MAPT) cDNA with the P301L mutation is under the control of the Camk2a promoter. (J:222897)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:222897 Matarin M, et al., A genome-wide gene-expression analysis and database in transgenic mice during development of amyloid or tau pathology. Cell Rep. 2015 Feb 3;10(4):633-44
• All: 3 reference(s)