Tg(PDGFB-SNCA*A53T)8Ema
Transgene Detail

Summary

• Symbol: Tg(PDGFB-SNCA*A53T)8Ema
• Name: transgene insertion 8, Eliezer Masliah
• MGI ID: MGI:5699838
• Transgene: Tg(PDGFB-SNCA*A53T)8Ema Location: unknown
• Alliance: Tg(PDGFB-SNCA*A53T)8Ema page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(PDGFB-SNCA*A53T)8Ema expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SNCA (6622)

  Snca	(MGI:1277151)

• Mutation details: The human alpha-synuclein gene with the A53T mutation is under the control of the human platelet-derived growth factor beta promoter. (J:227112)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:227112 Hashimoto M, et al., Transgenic models of alpha-synuclein pathology: past, present, and future. Ann N Y Acad Sci. 2003 Jun;991:171-88
• All: 2 reference(s)