Tg(SRY-YFP,Tyr)TashTNpln
Transgene Detail

Summary

• Symbol: Tg(SRY-YFP,Tyr)TashTNpln
• Name: transgene insertion TashT, Nicolas Pilon
• MGI ID: MGI:5755287
• Synonyms: TashT^Tg
• Transgene: Tg(SRY-YFP,Tyr)TashTNpln Location: Chr10:45453925-49664862 bp Genetic Position: Chr10, Syntenic
• Alliance: Tg(SRY-YFP,Tyr)TashTNpln page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A transgenic construct containing YFP under the control of the 1.6Kb of the porcine SRY promoter was co-injected with a tyrosinase minigene at equimolar ratios into FVB/N embryos. Mapping indicates that the TashT line contains transgenes inserted within a 3.3 Mb gene dessert containing highly conserved elements on chromosome 10 at bands B2-B3, between Hace1 and Grik2. (J:224231)

Disease models

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:224231 Bergeron KF, et al., Male-biased aganglionic megacolon in the TashT mouse line due to perturbation of silencer elements in a large gene desert of chromosome 10. PLoS Genet. 2015 Mar;11(3):e1005093
• All: 4 reference(s)