Tg(Sp7-Mir188)1Xhl
Transgene Detail

Summary

• Symbol: Tg(Sp7-Mir188)1Xhl
• Name: transgene insertion 1, Xiang-Hang Luo
• MGI ID: MGI:5763034
• Synonyms: miR-188-Tg
• Transgene: Tg(Sp7-Mir188)1Xhl Location: unknown
• Alliance: Tg(Sp7-Mir188)1Xhl page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Sp7-Mir188)1Xhl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir188 (MGI:2676852)

• Mutation details: The osteoprogenitor-specific promoter drives expression of the mouse pre-microRNA. Two lines were generated (lines 1 and 2) with line 1 exhibiting 7-fold overexpression. (J:222099)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:222099 Li CJ, et al., MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest. 2015 Apr;125(4):1509-22
• All: 1 reference(s)