Tg(KRT19-TAg)7Eps
Transgene Detail

Summary

• Symbol: Tg(KRT19-TAg)7Eps
• Name: transgene insertion 7, Eric P Sandgren
• MGI ID: MGI:5789553
• Synonyms: CK19-TAg, TgN(Ck19Sv)7Eps
• Transgene: Tg(KRT19-TAg)7Eps Location: unknown
• Alliance: Tg(KRT19-TAg)7Eps page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The human cytokeratin 19 promoter drives expression of the simian virus 40 large T antigen (TAg) in simple epithelial cells including urothelial cells. Line 7 stems from the 1244-3 founder. (J:64395)

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:64395 Grippo PJ, et al., Highly invasive transitional cell carcinoma of the bladder in a simian virus 40 T-antigen transgenic mouse model. Am J Pathol. 2000 Sep;157(3):805-13
• All: 2 reference(s)