Tg(PyLT)1Vb
Transgene Detail

Summary

• Symbol: Tg(PyLT)1Vb
• Name: transgene insertion 1, Victoria L Bautch
• MGI ID: MGI:5805518
• Synonyms: PyLT-1
• Transgene: Tg(PyLT)1Vb Location: unknown
• Alliance: Tg(PyLT)1Vb page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The polyoma early region promotor drives the expression of the polyoma large T antigen cDNA that has a deletion in the late region and at the origin of replication that prevents autonomous replication. (J:55528)

Disease models

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:55528 Helseth A, et al., Transgenic mice that develop pituitary tumors. A model for Cushing's disease. Am J Pathol. 1992 May;140(5):1071-80
• All: 1 reference(s)