About   Help   FAQ
Tg(tetO-Nras*Q61K)#Lc
Transgene Detail
Summary
Symbol: Tg(tetO-Nras*Q61K)#Lc
Name: transgene insertion, Lynda Chin
MGI ID: MGI:5818045
Synonyms: TetO-iNRASQ61K
Transgene: Tg(tetO-Nras*Q61K)#Lc  Location: unknown  
Alliance: Tg(tetO-Nras*Q61K)#Lc page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe tetracycline operon drives the inducible expression of a cDNA with nucleotide substitutions that result in the amino acid substitution of lysine for glutamine at position 61 (Q61K). (J:238049)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:238049 Kwong LN, et al., Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med. 2012 Oct;18(10):1503-10
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory