Tg(Tcra-V19-J33)#Lantz
Transgene Detail

Summary

• Symbol: Tg(Tcra-V19-J33)#Lantz
• Name: transgene insertion, Olivier Lantz
• MGI ID: MGI:5829575
• Synonyms: iValpha19 TCRalpha chain Tg, iValpha19 Tg, mValpha19-Jalpha33 Tg, mValpha-Jalpha33 TCRalpha chain Tg
• Transgene: Tg(Tcra-V19-J33)#Lantz Location: unknown
• Alliance: Tg(Tcra-V19-J33)#Lantz page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The recombined T cell receptor alpha (Tcra) variable region sequence of a mucosal associated invariant T (MAIT) cell T-T hybridoma having the canonical invariant Tcra-V19-J33 rearrangement was inserted into a TCRalpha shuttle vector, which was then injected into mouse oocytes. (J:55844, J:90982, J:149748)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

Notes

# is used in the transgene symbol because the three transgenic founder lines that were analyzed are not distinguished from one another and data from all of them were pooled. (J:149748)

References

• Original: J:149748 Martin E, et al., Stepwise development of MAIT cells in mouse and human. PLoS Biol. 2009 Mar 10;7(3):e54
• All: 4 reference(s)