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Del(XMagea1-Magea6)1Nju Cytogenetic Marker Detail
Summary
  • Symbol
    Del(XMagea1-Magea6)1Nju
  • Name
    deletion, Chr X, Xiang Gao 1
  • Feature Type
    chromosomal deletion
  • IDs
    MGI:5898328
Location &
Maps
less
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome X, Syntenic
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Hemizygous deletion of this cluster in males results in smaller testes, increased apoptosis in spermatocytes and increased sensitivity to DNA damaging agents.
References
more
  • Summaries
    All 1
    Phenotypes 1
  • Earliest
    J:240206 Hou S, et al., The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice. Sci Rep. 2016 May 26;6:26735
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory