Rr198 Other Genome Feature Detail

Summary

• Symbol
  Rr198
• Name
  regulatory region 198
• Synonyms
  CS1, Igs20

• Feature Type
  imprinting control region
• IDs
  MGI:5907834
• Member of
  Igdmr cluster

Location &
Maps

• Sequence Map
  Chr12:109489982-109490419 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI
• From seq in figure 2 in J:241393. Chr2:109489982-109490419 (GRCm39)

• Genetic Map
  Chromosome 12, Syntenic

Strain
Comparison

• SNPs within 2kb
  110 from dbSNP Build 142

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  0 strains or lines available

Heterozygous knockout mice show a mild effect on epigenetic expression regulation of downstream genes in a parent of origin specific allele manner.

References

• Summaries
  All 2

  Phenotypes 1
• Earliest
  J:241393 Saito T, et al., Deletion of conserved sequences in IG-DMR at Dlk1-Gtl2 locus suggests their involvement in expression of paternally expressed genes in mice. J Reprod Dev. 2017 Feb 16;63(1):101-109