Del(XMageb5)1Jbmu Cytogenetic Marker Detail

Summary

• Symbol
  Del(XMageb5)1Jbmu
• Name
  deletion, chr X, Jacob Mueller 1

• Feature Type
  chromosomal deletion
• IDs
  MGI:6111072

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome X, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from multigenic genotypes
  2 phenotype references
  

• All Mutations and Alleles
  1
• Endonuclease-mediated
  1
• Find Mice (IMSR)
  3 strains or lines available

Mice hemizygous for a deletion of a 30 kb deletion including Mageb5 and a null allele of Mageb5b exhibit normal male fertility despite slightly elongated sperm.

References

• Summaries
  All 3

  Phenotypes 2
• Earliest
  J:263809 Kruger AN, et al., Male mice with large inversions or deletions of X-chromosome palindrome arms are fertile and express their associated genes during post-meiosis. Sci Rep. 2018 Jun 12;8(1):8985
• Latest
  J:334464 Stark-Dykema ER, et al., X-linked palindromic gene families 4930567H17Rik and Mageb5 are dispensable for male mouse fertility. Sci Rep. 2022 May 20;12(1):8554